No difference in growth Attenuated
Egress defect Invasion defect Transcriptional effect Cell-cycle arrest Altered cytoadherence
| Gene | Product | Disruptable |
Ase |
Gam |
Ook |
Ooc |
Spo |
Liv |
|---|---|---|---|---|---|---|---|---|
| PY17X_0203000 | early transcribed membrane protein (ETRAMP) | |||||||
| PY17X_0304500 | pantothenate transporter (PAT) | |||||||
| PY17X_0305600 | serine repeat antigen 2 (SERA2) | |||||||
| PY17X_0305700 | serine repeat antigen 1 (SERA1) | |||||||
| PY17X_0306600 | 6-cysteine protein (P230p) | |||||||
| PY17X_0405400 | circumsporozoite (CS) protein (CSP) | |||||||
| PY17X_0410700 | calcium-dependent protein kinase 3 (CDPK3) | |||||||
| PY17X_0415800 | circumsporozoite- and TRAP-related protein, putative (CTRP) | |||||||
| PY17X_0502100 | early transcribed membrane protein (ETRAMP) | |||||||
| PY17X_0502200 | early transcribed membrane protein (UIS4) | |||||||
| PY17X_0518000 | S-adenosylmethionine decarboxylase/ornithine decarboxylase (AdoMetDC/ODC) | |||||||
| PY17X_0518100 | early transcribed membrane protein (ETRAMP) | |||||||
| PY17X_0522400 | 18S ribosomal RNA | |||||||
| PY17X_0525600 | early transcribed membrane protein (Sep-02) | |||||||
| PY17X_0526200 | early transcribed membrane protein (Sep-01) | |||||||
| PY17X_0613900 | pantothenate kinase, putative | |||||||
| PY17X_0616300 | phosphopantothenate--cysteine ligase, putative | |||||||
| PY17X_0625700 | 18S ribosomal RNA | |||||||
| PY17X_0704800 | E3 ubiquitin-protein ligase, putative | |||||||
| PY17X_0712400 | BEM46-like protein (PBLP) | |||||||
| PY17X_0713100 | high mobility group protein B2 (HMGB2) | |||||||
| PY17X_0714900 | phosphopantothenoylcysteine decarboxylase, putative | |||||||
| PY17X_0715100 | dihydrolipoyl dehydrogenase, apicoplast, putative | |||||||
| PY17X_0719200 | mRNA-binding protein PUF2 (PUF2) | |||||||
| PY17X_0805100 | phosphopantetheine adenylyltransferase, putative (PPAT) | |||||||
| PY17X_0811300 | 6-cysteine protein | |||||||
| PY17X_0816300 | inhibitor of cysteine proteases (ICP) | |||||||
| PY17X_0903500 | sporozoite and liver stage asparagine-rich protein (SLARP) | |||||||
| PY17X_0925800 | pyruvate dehydrogenase E1 component subunit alpha, putative | |||||||
| PY17X_0934900 | glycerol-3-phosphate dehydrogenase (G3PDH) | |||||||
| PY17X_0935500 | rhomboid protease ROM1 (ROM1) | |||||||
| PY17X_0946500 | early transcribed membrane protein (ETRAMP) | |||||||
| PY17X_1000800 | early transcribed membrane protein (ETRAMP) | |||||||
| PY17X_1007700 | sporozoite micronemal protein essential for cell traversal (PLP1) | |||||||
| PY17X_1024500 | pantothenate kinase, putative | |||||||
| PY17X_1030600 | atypical protein kinase, ABC-1 family, putative | |||||||
| PY17X_1033500 | plastid replication-repair enzyme, putative (PREX) | |||||||
| PY17X_1114100 | purine nucleoside phosphorylase, putative (PNP) | |||||||
| PY17X_1123700 | MEI2-like RNA-binding protein (PlasMei2) | |||||||
| PY17X_1126500 | 3-oxoacyl-acyl-carrier protein synthase, putative (FabB/FabF) | |||||||
| PY17X_1148500 | early transcribed membrane protein (ETRAMP) | |||||||
| PY17X_1202100 | early transcribed membrane protein (ETRAMP) | |||||||
| PY17X_1210000 | zinc finger C-x8-C-x5-C-x3-H type, putative | |||||||
| PY17X_1310300 | TRAP-like protein (TREP) | |||||||
| PY17X_1311400 | dephospho-CoA kinase, putative (DPCK) | |||||||
| PY17X_1312000 | 1-acyl-sn-glycerol-3-phosphate acyltransferase (LPAAT) | |||||||
| PY17X_1337400 | duffy-binding protein | |||||||
| PY17X_1339000 | exported protein 2, putative (EXP2) | |||||||
| PY17X_1342900 | beta-hydroxyacyl-ACP dehydratase (FabZ) | |||||||
| PY17X_1354800 | thrombospondin-related anonymous protein (TRAP) | |||||||
| PY17X_1366000 | DNA/RNA-binding protein Alba 4, putative (ALBA4) | |||||||
| PY17X_1402400 | early transcribed membrane protein 13 (UIS3) | |||||||
| PY17X_1418400 | glycerol-3-phosphate 1-O-acyltransferase (G3PAT) | |||||||
| PY17X_1421600 | phosphodiesterase gamma (PDEgamma) | |||||||
| PY17X_1427200 | sporozoite surface protein 3 (SSP3) | |||||||
| PY17X_1446500 | macrophage migration inhibitory factor (MIF) | |||||||
| PY17X_1468100 | reticulocyte binding protein, putative (Py235) |