Disruptability [+]

Species Disruptability Reference Submitter
P. yoelii yoelii 17X
Refractory
RMgm-4376 Imported from RMgmDB
P. berghei ANKA
Refractory
RMgm-4089 Imported from RMgmDB
P. berghei ANKA
Refractory
PlasmoGEM (Barseq) PlasmoGEM

Mutant phenotypes [+]

None reported yet. Please press the '+' button above to add one.

Imaging data (from Malaria Metabolic Pathways)

PfAP2-I Is a Nuclear Protein that May Bind a Conserved TGCA DNA Motif Upstream of Some Invasion Genes. Live fluorescence microscopy of synchronized parasites shows that PfAP2-I-GFP (see Figure S1B) localizes to the nucleus of trophozoite and schizont stage parasites but is not detected in ring stages. Hoechst was used as a nuclear marker. Live microscopy and nuclear fractionation assays show that PfAP2-I localizes exclusively to the nucleus of trophozoite and schizont stage parasites.Santos JM, Josling G, Ross P, Joshi P, Orchard L, Campbell T, Schieler A, Cristea IM, Llinás M. Red Blood Cell Invasion by the Malaria Parasite Is Coordinated by the PfAP2-I Transcription Factor. Cell Host Microbe. 2017 21(6).

See original on MMP

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