Last updated 3 years ago

Disruptability [+]

Species Disruptability Reference Submitter
P. yoelii yoelii 17X
Possible
RMgm-4387 Imported from RMgmDB
P. yoelii yoelii 17X
Possible
RMgm-4979 Imported from RMgmDB
P. berghei ANKA
Possible
RMgm-4103 Imported from RMgmDB
P. berghei ANKA
Possible
RMgm-5254 Imported from RMgmDB
P. berghei ANKA
Possible
RMgm-5254 Imported from RMgmDB
P. berghei ANKA
Possible
RMgm-5254 Imported from RMgmDB
P. falciparum 3D7
Possible
18614010 Theo Sanderson, Wellcome Trust Sanger Institute
P. falciparum 3D7
Possible
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. yoelii yoelii 17X Asexual
No difference
RMgm-4387 Imported from RMgmDB
P. yoelii yoelii 17X Asexual
No difference
RMgm-4979 Imported from RMgmDB
P. yoelii yoelii 17X Gametocyte
No difference
RMgm-4387 Imported from RMgmDB
P. yoelii yoelii 17X Gametocyte
No difference
RMgm-4979 Imported from RMgmDB
P. yoelii yoelii 17X Ookinete
Difference from wild-type
RMgm-4387
Normal numbers of gametocytes are produced. Only ookinetes with aberrant morphology are produced.
Imported from RMgmDB
P. yoelii yoelii 17X Ookinete
Difference from wild-type
RMgm-4979
Normal numbers of gametocytes are produced. Normal exflagellation. Normal egress of gametes. Males are fertile (shown in crossing-experiments). Fertilization ability of females is impaired. Fertilized zygotes of the ap2-o3 mutants were developmentally arrested at the early stages (stage II-III), displaying incomplete elongation. Only ookinetes with aberrant morphology are produced.
Imported from RMgmDB
P. yoelii yoelii 17X Oocyst
Difference from wild-type
RMgm-4387
Normal numbers of gametocytes are produced. Only ookinetes with aberrant morphology are produced. No oocysts and salivary gland sporozoites are formed.
Imported from RMgmDB
P. yoelii yoelii 17X Sporozoite
Difference from wild-type
RMgm-4387
Normal numbers of gametocytes are produced. Only ookinetes with aberrant morphology are produced. No oocysts and salivary gland sporozoites are formed.
Imported from RMgmDB
P. berghei ANKA Asexual
No difference
RMgm-4103 Imported from RMgmDB
P. berghei ANKA Asexual
No difference
RMgm-5254 Imported from RMgmDB
P. berghei ANKA Asexual
No difference
RMgm-5254 Imported from RMgmDB
P. berghei ANKA Asexual
No difference
RMgm-5254 Imported from RMgmDB
P. berghei ANKA Gametocyte
No difference
RMgm-4103 Imported from RMgmDB
P. berghei ANKA Gametocyte
No difference
RMgm-5254 Imported from RMgmDB
P. berghei ANKA Gametocyte
No difference
RMgm-5254 Imported from RMgmDB
P. berghei ANKA Gametocyte
No difference
RMgm-5254 Imported from RMgmDB
P. berghei ANKA Ookinete
Difference from wild-type
RMgm-4103
Normal gametocyte production and gamete formation. Evidence for normal fertilisation. Formation of retort shaped, immature ookinetes but no mature ookinete production.The majority of zygotes failed to show apical complex protrusions.
Imported from RMgmDB
P. berghei ANKA Ookinete
Difference from wild-type
RMgm-5254
The mutant formed morphologically normal female and male gametocytes, and the male gametocytes showed normal exflagellation. Pbap2-fg2(-) parasites failed to produce banana-shaped ookinetes; more than half of the fertilized population stopped developing at round zygotes, and the others, at retort-form ookinetes.
Imported from RMgmDB
P. berghei ANKA Ookinete
Difference from wild-type
RMgm-5254
The mutant formed morphologically normal female and male gametocytes, and the male gametocytes showed normal exflagellation. Pbap2-fg2(-) parasites failed to produce banana-shaped ookinetes; more than half of the fertilized population stopped developing at round zygotes, and the others, at retort-form ookinetes.
Imported from RMgmDB
P. berghei ANKA Ookinete
Difference from wild-type
RMgm-5254
The mutant formed morphologically normal female and male gametocytes, and the male gametocytes showed normal exflagellation. Pbap2-fg2(-) parasites failed to produce banana-shaped ookinetes; more than half of the fertilized population stopped developing at round zygotes, and the others, at retort-form ookinetes.
Imported from RMgmDB
P. berghei ANKA Oocyst
Difference from wild-type
RMgm-4103
No mature ookinete production. No oocyst production.
Imported from RMgmDB
P. berghei ANKA Oocyst
Difference from wild-type
RMgm-5254
Formation of aberrant ookinetes. No oocyst/sporozoite formation
Imported from RMgmDB
P. berghei ANKA Oocyst
Difference from wild-type
RMgm-5254
Formation of aberrant ookinetes. No oocyst/sporozoite formation
Imported from RMgmDB
P. berghei ANKA Oocyst
Difference from wild-type
RMgm-5254
Formation of aberrant ookinetes. No oocyst/sporozoite formation
Imported from RMgmDB
P. berghei ANKA Sporozoite
Difference from wild-type
RMgm-5254
Formation of aberrant ookinetes. No oocyst/sporozoite formation
Imported from RMgmDB
P. berghei ANKA Sporozoite
Difference from wild-type
RMgm-5254
Formation of aberrant ookinetes. No oocyst/sporozoite formation
Imported from RMgmDB
P. berghei ANKA Sporozoite
Difference from wild-type
RMgm-5254
Formation of aberrant ookinetes. No oocyst/sporozoite formation
Imported from RMgmDB

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