Last updated 3 years ago

Disruptability [+]

Species Disruptability Reference Submitter
P. yoelii yoelii 17X
Possible
RMgm-4788 Imported from RMgmDB
P. berghei ANKA
Possible
RMgm-1373 Imported from RMgmDB
P. berghei ANKA
Possible
PlasmoGEM (Barseq) PlasmoGEM
P. falciparum 3D7
Possible
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen
P. falciparum 3D7
Possible
35404116
\"For PfCDF-TGD, the correct integration of the plasmid into the genomic locus was also verified, but wild-type DNA was still detectable and remained even upon prolonged culturing under G418/WR selection and limited dilution cloning\"
Theo Sanderson, Francis Crick Institute

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. yoelii yoelii 17X Asexual
No difference
RMgm-4788 Imported from RMgmDB
P. yoelii yoelii 17X Gametocyte
Difference from wild-type
RMgm-4788
normal production of gametocytes; normal exflagellation
Imported from RMgmDB
P. berghei ANKA Asexual
No difference
RMgm-1373 Imported from RMgmDB
P. berghei ANKA Asexual
No difference
PlasmoGEM (Barseq) PlasmoGEM
P. berghei ANKA Gametocyte
Difference from wild-type
RMgm-1373
Strongly reduced exflagellation
Imported from RMgmDB
P. berghei ANKA Ookinete
Difference from wild-type
RMgm-1373
Strongly reduced ookinete numbers
Imported from RMgmDB
P. berghei ANKA Sporozoite
Difference from wild-type
RMgm-1373
Strongly reduced sporozoite numbers in vivo
Imported from RMgmDB
P. berghei ANKA Liver
Difference from wild-type
RMgm-1373
Delayed transmission in vivo
Imported from RMgmDB

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