Disruptability [+]

Species Disruptability Reference Submitter
P. yoelii yoelii 17X
Possible
RMgm-1107 Imported from RMgmDB
P. berghei ANKA
Possible
PlasmoGEM (Barseq) PlasmoGEM
P. falciparum 3D7
Possible
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. yoelii yoelii 17X Asexual
No difference
RMgm-1107 Imported from RMgmDB
P. yoelii yoelii 17X Gametocyte
No difference
RMgm-1107 Imported from RMgmDB
P. yoelii yoelii 17X Ookinete
No difference
RMgm-1107 Imported from RMgmDB
P. yoelii yoelii 17X Oocyst
No difference
RMgm-1107 Imported from RMgmDB
P. yoelii yoelii 17X Sporozoite
Difference from wild-type
RMgm-1107
Normal numbers of sporozoites are formed. Gliding motility is affected. Sporozoites showed normal hepatocyte traversal and invasion in vitro. Hepatocyte invasion and liver stage development in vivo was comparable to wild type parasites.
Imported from RMgmDB
P. yoelii yoelii 17X Liver
Difference from wild-type
RMgm-1107
Normal numbers of sporozoites are formed. Gliding motility is affected. Sporozoites showed normal hepatocyte traversal and invasion in vitro. Hepatocyte invasion and liver stage development in vivo was comparable to wild type parasites.
Imported from RMgmDB

More information