Disruptability [+]

Species Disruptability Reference Submitter
P. yoelii yoelii 17X
Possible
RMgm-1496 Imported from RMgmDB
P. berghei ANKA
Refractory
PlasmoGEM (Barseq) PlasmoGEM
P. falciparum 3D7
Refractory
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. yoelii yoelii 17X Asexual
Difference from wild-type
RMgm-1496
Reduced growth/asexual multiplication in mice. (Light-microscopic) morphology of blood stages was not different from wild type.
Imported from RMgmDB
P. yoelii yoelii 17X Gametocyte
Difference from wild-type
RMgm-1496
Reduced gametocyte production. Reduction in male gametocytes higher than in female gametocytes. Reduced male gamete formation (male gametogenesis/exflagellation).
Imported from RMgmDB
P. yoelii yoelii 17X Ookinete
Difference from wild-type
RMgm-1496
No ookinete formation in A. stephensi mosquitoes
Imported from RMgmDB
P. yoelii yoelii 17X Oocyst
Difference from wild-type
RMgm-1496
No oocyst formation in A. stephensi mosquitoes
Imported from RMgmDB
P. yoelii yoelii 17X Sporozoite
Difference from wild-type
RMgm-1496
No sporozoite formation in A. stephensi mosquitoes
Imported from RMgmDB

More information