Disruptability [+]

Species Disruptability Reference Submitter
P. berghei ANKA
Possible
RMgm-753 Imported from RMgmDB
P. berghei ANKA
Possible
PlasmoGEM (Barseq) PlasmoGEM
P. berghei ANKA
Possible
RMgm-4620 Imported from RMgmDB
P. falciparum 3D7
Possible
25843709 Theo Sanderson, Wellcome Trust Sanger Institute
P. falciparum 3D7
Refractory
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. berghei ANKA Asexual
No difference
RMgm-753 Imported from RMgmDB
P. berghei ANKA Asexual
No difference
RMgm-4620 Imported from RMgmDB
P. falciparum 3D7 Asexual
No difference
25843709 Theo Sanderson, Wellcome Trust Sanger Institute
P. berghei ANKA Gametocyte
Difference from wild-type
RMgm-753
Normal numbers of gametocytes are produced and male gamete formation (exflagellation) was normal. The conversion rate of female gametes to ookinetes in vitro of Pbsdha(-) was significantly reduced to 17% of wild type parasites.
Imported from RMgmDB
P. berghei ANKA Ookinete
Difference from wild-type
RMgm-753
The conversion rate of female gametes to ookinetes in vitro of Pbsdha(-) was significantly reduced to 17% of wild type parasites.
Imported from RMgmDB
P. berghei ANKA Oocyst
Difference from wild-type
RMgm-753
The conversion rate of female gametes to ookinetes in vitro of Pbsdha(-) was significantly reduced to 17% of wild type parasites.No oocysts are formed.
Imported from RMgmDB
P. berghei ANKA Oocyst
Difference from wild-type
RMgm-4620
No formation of oocysts
Imported from RMgmDB
P. berghei ANKA Sporozoite
Difference from wild-type
RMgm-4620
No formation of oocysts; no formation of salivary gland sporozoites
Imported from RMgmDB
P. berghei ANKA Liver
Difference from wild-type
RMgm-4620
See Additional Information: Evidence for a role during liver stage development
Imported from RMgmDB

More information