Last updated 3 years ago

Disruptability [+]

Species Disruptability Reference Submitter
P. falciparum 3D7
Possible
25843709 Theo Sanderson, Wellcome Trust Sanger Institute
P. falciparum 3D7
Refractory
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen
P. berghei ANKA
Possible
RMgm-753 Imported from RMgmDB
P. berghei ANKA
Possible
PlasmoGEM (Barseq) PlasmoGEM
P. berghei ANKA
Possible
RMgm-4620 Imported from RMgmDB

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. falciparum 3D7 Asexual
No difference
25843709 Theo Sanderson, Wellcome Trust Sanger Institute
P. berghei ANKA Asexual
No difference
RMgm-753 Imported from RMgmDB
P. berghei ANKA Asexual
No difference
RMgm-4620 Imported from RMgmDB
P. berghei ANKA Gametocyte
Difference from wild-type
RMgm-753
Normal numbers of gametocytes are produced and male gamete formation (exflagellation) was normal. The conversion rate of female gametes to ookinetes in vitro of Pbsdha(-) was significantly reduced to 17% of wild type parasites.
Imported from RMgmDB
P. berghei ANKA Ookinete
Difference from wild-type
RMgm-753
The conversion rate of female gametes to ookinetes in vitro of Pbsdha(-) was significantly reduced to 17% of wild type parasites.
Imported from RMgmDB
P. berghei ANKA Oocyst
Difference from wild-type
RMgm-753
The conversion rate of female gametes to ookinetes in vitro of Pbsdha(-) was significantly reduced to 17% of wild type parasites.No oocysts are formed.
Imported from RMgmDB
P. berghei ANKA Oocyst
Difference from wild-type
RMgm-4620
No formation of oocysts
Imported from RMgmDB
P. berghei ANKA Sporozoite
Difference from wild-type
RMgm-4620
No formation of oocysts; no formation of salivary gland sporozoites
Imported from RMgmDB
P. berghei ANKA Liver
Difference from wild-type
RMgm-4620
See Additional Information: Evidence for a role during liver stage development
Imported from RMgmDB

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