PKNH_0403800 ATP synthase F1, alpha subunit, putative
Disruptability [+]
| Species | Disruptability | Reference | Submitter | |
|---|---|---|---|---|
| P. berghei ANKA |
Possible |
PlasmoGEM (Barseq) | PlasmoGEM | |
| P. falciparum 3D7 |
Refractory |
USF piggyBac screen (Insert. mut.) | USF PiggyBac Screen | |
Mutant phenotypes [+]
| Species | Stage | Phenotype | Reference | Submitter |
|---|---|---|---|---|
| P. berghei ANKA | Asexual |
Attenuated |
PlasmoGEM (Barseq) | PlasmoGEM |
Imaging data (from Malaria Metabolic Pathways)
Localization of epitope-tagged ATP synthase subunits detected using immuno-fluoresence microscopy. Immunofluoresence of alpha, gamma, delta, epsilon, OSCP and c subunits expressed under control of the mRPL2 promoter. Expression of the beta subunit was under the control of its own promoter. Green fluorescence: Anti-HA antibody (AlexaFluor 488-conjugated secondary antibody). Red fluorescence: Mitotracker Red CM-H2XRos. Blue fluorescence: DAPI (4'-6-Diamidino-2-phenylindole). DIC: Differential interference contrast microscopy.Balabaskaran Nina P, Morrisey JM, Ganesan SM, Ke H, Pershing AM, Mather MW, Vaidya AB. ATP synthase complex of Plasmodium falciparum: dimeric assembly in mitochondrial membranes and resistance to genetic disruption. J Biol Chem. 2011 286(48):41312-22. PMID:
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| PlasmoDB | PKNH_0403800 |
| GeneDB | PKNH_0403800 |
| Malaria Metabolic Pathways | Localisation images Pathways mapped to |
| Previous ID(s) | PK2_1570w, PKH_040300 |
| Orthologs | PBANKA_0313800 , PCHAS_0315900 , PF3D7_0217100 , PVP01_0407900 , PVX_002685 , PY17X_0314300 |
| Google Scholar | Search for all mentions of this gene |