Disruptability [+]

Species Disruptability Reference Submitter
P. falciparum 3D7
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen
P. berghei ANKA
PlasmoGEM (Barseq) PlasmoGEM

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. berghei ANKA Asexual
PlasmoGEM (Barseq) PlasmoGEM

Imaging data (from Malaria Metabolic Pathways)

Localization of epitope-tagged ATP synthase subunits detected using immuno-fluoresence microscopy. Immunofluoresence of alpha, gamma, delta, epsilon, OSCP and c subunits expressed under control of the mRPL2 promoter. Expression of the beta subunit was under the control of its own promoter. Green fluorescence: Anti-HA antibody (AlexaFluor 488-conjugated secondary antibody). Red fluorescence: Mitotracker Red CM-H2XRos. Blue fluorescence: DAPI (4'-6-Diamidino-2-phenylindole). DIC: Differential interference contrast microscopy.Balabaskaran Nina P, Morrisey JM, Ganesan SM, Ke H, Pershing AM, Mather MW, Vaidya AB. ATP synthase complex of Plasmodium falciparum: dimeric assembly in mitochondrial membranes and resistance to genetic disruption. J Biol Chem. 2011 286(48):41312-22. PMID:

See original on MMP

More information

PlasmoDB PF3D7_0217100
GeneDB PF3D7_0217100
Malaria Metabolic Pathways Localisation images
Pathways mapped to
Previous ID(s) PF02_0161, PFB0795w
Orthologs PBANKA_0313800 , PCHAS_0315900 , PKNH_0403800 , PVP01_0407900 , PVX_002685 , PY17X_0314300
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