| Species | Disruptability | Reference | Submitter | |
|---|---|---|---|---|
| P. berghei ANKA |
Possible |
RMgm-142 | Imported from RMgmDB | |
| P. berghei ANKA |
Possible |
PlasmoGEM (Barseq) | PlasmoGEM | |
| P. falciparum 3D7 |
Possible |
USF piggyBac screen (Insert. mut.) | USF PiggyBac Screen | |
| Species | Stage | Phenotype | Reference | Submitter |
|---|---|---|---|---|
| P. berghei ANKA | Asexual |
No difference |
RMgm-142 | Imported from RMgmDB |
| P. berghei ANKA | Asexual |
No difference |
PlasmoGEM (Barseq) | PlasmoGEM |
| P. berghei ANKA | Gametocyte |
No difference |
RMgm-142 | Imported from RMgmDB |
| P. berghei ANKA | Ookinete |
Difference from wild-type |
RMgm-142
Mutants developed gametocytes and formed ookinetes in vitro in similar numbers to, and morphologically indistinguishable from, wild type parasites in Giemsa-stained preparations. Reduced numbers of oocysts (reduction of 60-85%) are produced in A. stephensi mosquitoes. |
Imported from RMgmDB |
| P. berghei ANKA | Oocyst |
Difference from wild-type |
RMgm-142
Normal numbers of ookinetes are produced. Reduced numbers of oocysts (reduction of 60-85%) are produced in A. stephensi mosquitoes. Although oocyst numbers were markedly reduced in mutant-infected mosquitoes, those oocysts that developed were morphologically indistinguishable from wild type oocysts of comparable age, and formed large numbers of sporozoites similar to wild type oocysts. |
Imported from RMgmDB |
| P. berghei ANKA | Sporozoite |
Difference from wild-type |
RMgm-142
Mutant sporozoites appeared morphologically normal and successfully invaded the salivary glands. Mosquitoes that were infected with mutant sporozoites successfully transmitted the parasite to mice. |
Imported from RMgmDB |
| P. berghei ANKA | Liver |
Difference from wild-type |
RMgm-142
Mutant sporozoites appeared morphologically normal and successfully invaded the salivary glands. Mosquitoes that were infected with mutant sporozoites successfully transmitted the parasite to mice. |
Imported from RMgmDB |
| PlasmoDB | PCHAS_1038600 |
| GeneDB | PCHAS_1038600 |
| Malaria Metabolic Pathways | Localisation images Pathways mapped to |
| Previous ID(s) | PC000172.05.0, PCAS_103760, PCHAS_103860 |
| Orthologs | PBANKA_1037800 , PF3D7_1404300 , PKNH_1353800 , PVP01_1344500 , PVX_086220 , PY17X_1040200 |
| Google Scholar | Search for all mentions of this gene |