Species | Disruptability | Reference | Submitter | |
---|---|---|---|---|
P. berghei ANKA |
Possible |
RMgm-156 | Imported from RMgmDB | |
P. berghei ANKA |
Possible |
RMgm-155 | Imported from RMgmDB | |
P. berghei ANKA |
Possible |
PlasmoGEM (Barseq) | PlasmoGEM | |
P. berghei ANKA |
Possible |
RMgm-5344 | Imported from RMgmDB | |
P. berghei ANKA |
Possible |
RMgm-5344 | Imported from RMgmDB | |
P. falciparum 3D7 |
Possible |
USF piggyBac screen (Insert. mut.) | USF PiggyBac Screen | |
P. falciparum 3D7 |
Possible |
36241929 No difference in gam production, exflagellation, but males are infertile due to fertilisation defect |
Theo Sanderson, Francis Crick Institute |
Species | Stage | Phenotype | Reference | Submitter |
---|---|---|---|---|
P. berghei ANKA | Asexual |
No difference |
RMgm-156 | Imported from RMgmDB |
P. berghei ANKA | Asexual |
No difference |
RMgm-155 | Imported from RMgmDB |
P. berghei ANKA | Asexual |
No difference |
PlasmoGEM (Barseq) | PlasmoGEM |
P. berghei ANKA | Gametocyte |
Difference from wild-type |
RMgm-156
Normal numbers of male and female gametocytes are produced. Gamete formation was comparable to that of wild type parasites, as determined by light microscopy of exflagellation (male gamete formation) and escape of females from the host erythrocyte.Male gametes are sterile as shown by the lack of fertilisation when the mutant males are crossed with fertile female gametes. Mutant female gametes are fertile as shown by cross-fertilisation with wild type male gametes. |
Imported from RMgmDB |
P. berghei ANKA | Gametocyte |
Difference from wild-type |
RMgm-155
Normal numbers of male and female gametocytes are produced and the sex ratio was comparable to that of wild type gametocytes. Gamete formation was comparable to that of wild type parasites, as determined by light microscopy of exflagellation (male gamete formation) and escape of females from the host erythrocyte.Male gametes are sterile as shown by the lack of fertilisation when the mutant males are crossed with fertile female gametes. Mutant female gametes are fertile as shown by cross-fertilisation with wild type male gametes. |
Imported from RMgmDB |
P. berghei ANKA | Ookinete |
Difference from wild-type |
RMgm-156
Gamete formation was comparable to that of wild type parasites, as determined by light microscopy of exflagellation (male gamete formation) and escape of females from the host erythrocyte.Male gametes are sterile as shown by the lack of fertilisation when the mutant males are crossed with fertile female gametes. Mutant female gametes are fertile as shown by cross-fertilisation with wild type male gametes.Mutant males gametes showed flagella motility and adhesion to surrounding erythrocytes, forming exfagellating centers comparable to wild type. However, no successful entering of flagella into female gametes was observed. |
Imported from RMgmDB |
P. berghei ANKA | Ookinete |
Difference from wild-type |
RMgm-155
Gamete formation was comparable to that of wild type parasites, as determined by light microscopy of exflagellation (male gamete formation) and escape of females from the host erythrocyte.Male gametes are sterile as shown by the lack of fertilisation when the mutant males are crossed with fertile female gametes. Mutant female gametes are fertile as shown by cross-fertilisation with wild type male gametes.Mutant males attach to females but failed to progress from adhesion to membrane fusion and fertilization.No zygotes and ookinetes are formed. |
Imported from RMgmDB |
P. berghei ANKA | Oocyst |
Difference from wild-type |
RMgm-156
No ookinete and oocyst formation (see phenotype 'Fertilization and ookinete'). |
Imported from RMgmDB |
P. berghei ANKA | Oocyst |
Difference from wild-type |
RMgm-155
No ookinete and oocyst formation (see phenotype 'Fertilization and ookinete'). |
Imported from RMgmDB |
P. berghei ANKA | Sporozoite |
Difference from wild-type |
RMgm-156
No sporozoite formation (see phenotype 'Fertilization and ookinete' and 'Oocyst'). |
Imported from RMgmDB |
P. berghei ANKA | Liver |
No difference |
RMgm-156 | Imported from RMgmDB |
P. falciparum 3D7 | Asexual |
No difference |
36241929 No difference in gam production, exflagellation, but males are infertile due to fertilisation defect |
Theo Sanderson, Francis Crick Institute |
P. falciparum 3D7 | Gametocyte |
Difference from wild-type |
36241929 No difference in gam production, exflagellation, but males are infertile due to fertilisation defect |
Theo Sanderson, Francis Crick Institute |
PlasmoDB | PBANKA_1212600 |
GeneDB | PBANKA_1212600 |
Malaria Metabolic Pathways | Localisation images Pathways mapped to |
Previous ID(s) | PB000710.01.0, PB301553.00.0, PBANKA_121260 |
Orthologs | PCHAS_1213300 , PF3D7_1014200 , PKNH_0814100 , PVP01_0814300 , PVX_094925 , PY17X_1215800 |
Google Scholar | Search for all mentions of this gene |