| Species | Disruptability | Reference | Submitter | |
|---|---|---|---|---|
| P. berghei ANKA |
Possible |
RMgm-1374 | Imported from RMgmDB | |
| P. berghei ANKA |
Possible |
RMgm-307 | Imported from RMgmDB | |
| P. berghei ANKA |
Possible |
RMgm-169 | Imported from RMgmDB | |
| P. berghei ANKA |
Possible |
PlasmoGEM (Barseq) | PlasmoGEM | |
| P. falciparum 3D7 |
Possible |
18452584 | Theo Sanderson, Wellcome Trust Sanger Institute | |
| P. falciparum 3D7 |
Possible |
USF piggyBac screen (Insert. mut.) | USF PiggyBac Screen | |
| P. yoelii yoelii 17X |
Possible |
RMgm-4509 | Imported from RMgmDB | |
| P. yoelii yoelii 17X |
Possible |
RMgm-4795 | Imported from RMgmDB | |
| Species | Stage | Phenotype | Reference | Submitter |
|---|---|---|---|---|
| P. berghei ANKA | Asexual |
No difference |
RMgm-1374 | Imported from RMgmDB |
| P. berghei ANKA | Asexual |
No difference |
RMgm-307 | Imported from RMgmDB |
| P. berghei ANKA | Asexual |
No difference |
RMgm-169 | Imported from RMgmDB |
| P. berghei ANKA | Asexual |
Attenuated |
PlasmoGEM (Barseq) | PlasmoGEM |
| P. berghei ANKA | Gametocyte |
No difference |
RMgm-1374 | Imported from RMgmDB |
| P. berghei ANKA | Gametocyte |
No difference |
RMgm-307 | Imported from RMgmDB |
| P. berghei ANKA | Gametocyte |
No difference |
RMgm-169 | Imported from RMgmDB |
| P. berghei ANKA | Ookinete |
Difference from wild-type |
RMgm-307
Normal fertilisation rates and ookinete production. Ookinetes had a strongly reduced capacity to develop into oocysts (an oocyst production in Anopheles stephensi of only 2.2% of wild type oocysts). Mutant ookinetes had a greatly reduced gliding motility (speed). |
Imported from RMgmDB |
| P. berghei ANKA | Ookinete |
Difference from wild-type |
RMgm-169
Normal fertilisation rates and ookinete production. Ookinetes are not able to penetrate the cells of the midgut wall. The motility of ookinetes was reduced. The moving velocity of mutant parasites was much slower than that of wild type (wild type = 5.7 1.4 m/min, mutant = 0.6 0.1m/min) |
Imported from RMgmDB |
| P. berghei ANKA | Oocyst |
Difference from wild-type |
RMgm-307
Ookinetes had a strongly reduced capacity to develop into oocysts (an oocyst production in Anopheles stephensi of only 2.2% of wild type oocysts). Mutant ookinetes had a greatly reduced gliding motility (speed). |
Imported from RMgmDB |
| P. berghei ANKA | Oocyst |
Difference from wild-type |
RMgm-169
No oocyst formation. |
Imported from RMgmDB |
| P. berghei ANKA | Sporozoite |
Difference from wild-type |
RMgm-1374
No sporozoites in vivo |
Imported from RMgmDB |
| P. berghei ANKA | Liver |
Difference from wild-type |
RMgm-1374
No transmission by bite of infected mosquitoes |
Imported from RMgmDB |
| P. yoelii yoelii 17X | Asexual |
No difference |
RMgm-4795 | Imported from RMgmDB |
| P. falciparum 3D7 | Gametocyte |
No difference |
18452584 | Theo Sanderson, Wellcome Trust Sanger Institute |
| P. yoelii yoelii 17X | Gametocyte |
Difference from wild-type |
RMgm-4795
(somewhat) reduced production of gametocytes; normal exflagellation |
Imported from RMgmDB |
| PlasmoDB | PBANKA_1136700 |
| GeneDB | PBANKA_1136700 |
| Malaria Metabolic Pathways | Localisation images Pathways mapped to |
| Previous ID(s) | PB000752.03.0, PB001059.02.0, PB300849.00.0, PBANKA_113670, PbGCbeta |
| Orthologs | PCHAS_1136200 , PF3D7_1360500 , PKNH_1110800 , PVP01_1111400 , PVX_114990 , PY17X_1138200 |
| Google Scholar | Search for all mentions of this gene |