Disruptability [+]

Species Disruptability Reference Submitter
P. berghei ANKA
Refractory
PlasmoGEM (Barseq) PlasmoGEM
P. berghei ANKA
Possible
RMgm-4331 Imported from RMgmDB
P. berghei ANKA
Refractory
RMgm-4994 Imported from RMgmDB
P. falciparum 3D7
Refractory
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen
P. yoelii yoelii 17X
Refractory
RMgm-4802 Imported from RMgmDB

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. berghei ANKA Asexual
Difference from wild-type
RMgm-4331
Evidence is presented that the gene can be targeted for deletion indicating a non-essential role for blood stage growth/multiplication. However, see also RMgm-3980 for negative attempts to delete/disrupt this gene.
Imported from RMgmDB
P. falciparum 3D7 Asexual
Egress defect
33762339 (Conditional)
PfICM1-null schizonts exhibited an abnormal phenotype, with either complete loss of egress or rounding up with increased intracellular merozoite mobility
Abhinay Ramaprasad, The Francis Crick Institute

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