Last updated 1 year ago

Disruptability [+]

Species Disruptability Reference Submitter
P. falciparum 3D7
Refractory
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen
P. berghei ANKA
Refractory
PlasmoGEM (Barseq) PlasmoGEM
P. berghei ANKA
Possible
RMgm-4331 Imported from RMgmDB
P. berghei ANKA
Refractory
RMgm-4994 Imported from RMgmDB
P. yoelii yoelii 17X
Refractory
RMgm-4802 Imported from RMgmDB

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. falciparum 3D7 Asexual
Egress defect
33762339 (Conditional)
PfICM1-null schizonts exhibited an abnormal phenotype, with either complete loss of egress or rounding up with increased intracellular merozoite mobility
Abhinay Ramaprasad, The Francis Crick Institute
P. berghei ANKA Asexual
Difference from wild-type
RMgm-4331
Evidence is presented that the gene can be targeted for deletion indicating a non-essential role for blood stage growth/multiplication. However, see also RMgm-3980 for negative attempts to delete/disrupt this gene.
Imported from RMgmDB

More information

PlasmoDB PF3D7_1231400
GeneDB PF3D7_1231400
Malaria Metabolic Pathways Localisation images
Pathways mapped to
Previous ID(s) 2277.t00303, MAL12P1.303, PFL1515c
Orthologs PBANKA_1446100 , PCHAS_1448300 , PKNH_1450800 , PVP01_1449600 , PVX_100515 , PY17X_1448600
Google Scholar Search for all mentions of this gene