PKNH_1421400 dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, putative
Disruptability [+]
| Species | Disruptability | Reference | Submitter | |
|---|---|---|---|---|
| P. berghei ANKA |
Possible |
PlasmoGEM (Barseq) | PlasmoGEM | |
| P. falciparum 3D7 |
Possible |
USF piggyBac screen (Insert. mut.) | USF PiggyBac Screen | |
Mutant phenotypes [+]
| Species | Stage | Phenotype | Reference | Submitter |
|---|---|---|---|---|
| P. berghei ANKA | Asexual |
No difference |
PlasmoGEM (Barseq) | PlasmoGEM |
Imaging data (from Malaria Metabolic Pathways)
BCDH and KDH localization (A) Epifluorescent images of live P. falciparum erythrocytic-stage parasites expressing GFP fused to either the BCDH leader peptide (E2-BCDH30) or the KDH leader peptide (E2-KDH30). The parasites were stained with MitoTracker to identify mitochondria and Hoescht to identify nuclei. Image z-stacks were deconvolved and then presented as a single combined image. In both cases, GFP fluorescence co-localizes with MitoTracker to the mitochondrion. Afanador GA, Matthews KA, Bartee D, Gisselberg JE, Walters MS, Freel Meyers CL, Prigge ST. Redox-dependent lipoylation of mitochondrial proteins in Plasmodium falciparum. Mol Microbiol. 2014 Aug 13. [Epub ahead of print]
See original on MMPMore information
| PlasmoDB | PKNH_1421400 |
| GeneDB | PKNH_1421400 |
| Malaria Metabolic Pathways | Localisation images Pathways mapped to |
| Previous ID(s) | PK13_2030w, PKH_141980 |
| Orthologs | PBANKA_1419100 , PCHAS_1420900 , PF3D7_1320800 , PVP01_1421600 , PVX_122850 , PY17X_1420700 , PY17X_1420800 |
| Google Scholar | Search for all mentions of this gene |