Disruptability [+]

Species Disruptability Reference Submitter
P. falciparum 3D7
Possible
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen
P. berghei ANKA
Possible
PlasmoGEM (Barseq) PlasmoGEM

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. berghei ANKA Asexual
No difference
PlasmoGEM (Barseq) PlasmoGEM

Imaging data (from Malaria Metabolic Pathways)

BCDH and KDH localization (A) Epifluorescent images of live P. falciparum erythrocytic-stage parasites expressing GFP fused to either the BCDH leader peptide (E2-BCDH30) or the KDH leader peptide (E2-KDH30). The parasites were stained with MitoTracker to identify mitochondria and Hoescht to identify nuclei. Image z-stacks were deconvolved and then presented as a single combined image. In both cases, GFP fluorescence co-localizes with MitoTracker to the mitochondrion. Afanador GA, Matthews KA, Bartee D, Gisselberg JE, Walters MS, Freel Meyers CL, Prigge ST. Redox-dependent lipoylation of mitochondrial proteins in Plasmodium falciparum. Mol Microbiol. 2014 Aug 13. [Epub ahead of print]

See original on MMP

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