Disruptability [+]

Species Disruptability Reference Submitter
P. berghei ANKA
Possible
PlasmoGEM (Barseq) PlasmoGEM
P. falciparum 3D7
Possible
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. berghei ANKA Asexual
No difference
PlasmoGEM (Barseq) PlasmoGEM

Imaging data (from Malaria Metabolic Pathways)

Localization of PfUvrD. Immunofluorescence staining. The cells were fixed and immunostained. Panel (i) phase (ii) image of cell stained with DAPI (iii) immunofluorescently stained cell (green, P. falciparum UvrD) (iv) immunofluorescently stained cell (red, P. falciparum MLH) and (v) super-imposed images. Both proteins co-localize in the nucleus in a cell cycle-dependent manner with peak expression in the schizont stages of the development.Ahmad M, Ansari A, Tarique M, Satsangi AT, Tuteja R. Plasmodium falciparum UvrD Helicase Translocates in 3' to 5' Direction, Colocalizes with MLH and Modulates Its Activity through Physical Interaction. PLoS One. 2012;7(11):e49385.

See original on MMP

More information

PlasmoDB PKNH_1019000
GeneDB PKNH_1019000
Malaria Metabolic Pathways Localisation images
Pathways mapped to
Previous ID(s) PK5_1360c, PKH_101840
Orthologs PBANKA_1113800 , PCHAS_1113400 , PF3D7_0514100 , PVP01_1019800 , PVX_080535 , PY17X_1114900
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