PF3D7_0514100 ATP-dependent DNA helicase UvrD (UvrD)
Disruptability [+]
| Species | Disruptability | Reference | Submitter | |
|---|---|---|---|---|
| P. falciparum 3D7 |
Possible |
USF piggyBac screen (Insert. mut.) | USF PiggyBac Screen | |
| P. berghei ANKA |
Possible |
PlasmoGEM (Barseq) | PlasmoGEM | |
Mutant phenotypes [+]
| Species | Stage | Phenotype | Reference | Submitter |
|---|---|---|---|---|
| P. berghei ANKA | Asexual |
No difference |
PlasmoGEM (Barseq) | PlasmoGEM |
Imaging data (from Malaria Metabolic Pathways)
Localization of PfUvrD. Immunofluorescence staining. The cells were fixed and immunostained. Panel (i) phase (ii) image of cell stained with DAPI (iii) immunofluorescently stained cell (green, P. falciparum UvrD) (iv) immunofluorescently stained cell (red, P. falciparum MLH) and (v) super-imposed images. Both proteins co-localize in the nucleus in a cell cycle-dependent manner with peak expression in the schizont stages of the development.Ahmad M, Ansari A, Tarique M, Satsangi AT, Tuteja R. Plasmodium falciparum UvrD Helicase Translocates in 3' to 5' Direction, Colocalizes with MLH and Modulates Its Activity through Physical Interaction. PLoS One. 2012;7(11):e49385.
See original on MMPMore information
| PlasmoDB | PF3D7_0514100 |
| GeneDB | PF3D7_0514100 |
| Malaria Metabolic Pathways | Localisation images Pathways mapped to |
| Previous ID(s) | MAL5P1.142, PFE0705c |
| Orthologs | PBANKA_1113800 , PCHAS_1113400 , PKNH_1019000 , PVP01_1019800 , PVX_080535 , PY17X_1114900 |
| Google Scholar | Search for all mentions of this gene |