PKNH_0807000 histone deacetylase 2, putative (HDA2)
Disruptability [+]
| Species | Disruptability | Reference | Submitter | |
|---|---|---|---|---|
| P. berghei ANKA |
Refractory |
PlasmoGEM (Barseq) | PlasmoGEM | |
| P. falciparum 3D7 |
Refractory |
25121747 | Theo Sanderson, Wellcome Trust Sanger Institute | |
| P. falciparum 3D7 |
Refractory |
USF piggyBac screen (Insert. mut.) | USF PiggyBac Screen | |
Mutant phenotypes [+]
| Species | Stage | Phenotype | Reference | Submitter |
|---|---|---|---|---|
| P. falciparum 3D7 | Asexual |
Refractory |
25121747 (Conditional) | Theo Sanderson, Wellcome Trust Sanger Institute |
Imaging data (from Malaria Metabolic Pathways)
PfHda2 Is an Essential Nuclear Histone Deacetylase. (B) Immunofluorescence detection of PfHda2-HA in the perinuclear region of late stage asexual P. falciparum. Scale bar, 3 mm. (D) Immunofluorescence did not detect PfHda2-HA in merozoites costained with anti-GAP45.Coleman BI, Skillman KM, Jiang RH, Childs LM, Altenhofen LM, Ganter M, Leung Y, Goldowitz I, Kafsack BF, Marti M, Llinás M, Buckee CO, Duraisingh MT. A Plasmodium falciparum Histone Deacetylase Regulates Antigenic Variation and Gametocyte Conversion. Cell Host Microbe. 2014 16(2):177-86. PMID:
See original on MMPMore information
| PlasmoDB | PKNH_0807000 |
| GeneDB | PKNH_0807000 |
| Malaria Metabolic Pathways | Localisation images Pathways mapped to |
| Previous ID(s) | PK10_0630w, PKH_080680 |
| Orthologs | PBANKA_1206200 , PCHAS_1206900 , PF3D7_1008000 , PVP01_0807700 , PVX_094595 , PY17X_1209400 |
| Google Scholar | Search for all mentions of this gene |