Disruptability [+]

Species Disruptability Reference Submitter
P. berghei ANKA
Refractory
PlasmoGEM (Barseq) PlasmoGEM
P. falciparum 3D7
Refractory
25121747 Theo Sanderson, Wellcome Trust Sanger Institute
P. falciparum 3D7
Refractory
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. falciparum 3D7 Asexual
Refractory
25121747 (Conditional) Theo Sanderson, Wellcome Trust Sanger Institute

Imaging data (from Malaria Metabolic Pathways)

PfHda2 Is an Essential Nuclear Histone Deacetylase. (B) Immunofluorescence detection of PfHda2-HA in the perinuclear region of late stage asexual P. falciparum. Scale bar, 3 mm. (D) Immunofluorescence did not detect PfHda2-HA in merozoites costained with anti-GAP45.Coleman BI, Skillman KM, Jiang RH, Childs LM, Altenhofen LM, Ganter M, Leung Y, Goldowitz I, Kafsack BF, Marti M, Llinás M, Buckee CO, Duraisingh MT. A Plasmodium falciparum Histone Deacetylase Regulates Antigenic Variation and Gametocyte Conversion. Cell Host Microbe. 2014 16(2):177-86. PMID:

See original on MMP

More information

PlasmoDB PCHAS_1206900
GeneDB PCHAS_1206900
Malaria Metabolic Pathways Localisation images
Pathways mapped to
Previous ID(s) PC000326.03.0, PC000398.04.0, PC000401.01.0, PC300065.00.0, PCAS_120690, PCHAS_120690
Orthologs PBANKA_1206200 , PF3D7_1008000 , PKNH_0807000 , PVP01_0807700 , PVX_094595 , PY17X_1209400
Google Scholar Search for all mentions of this gene