Disruptability [+]

Species Disruptability Reference Submitter
P. berghei ANKA
Refractory
RMgm-4540 Imported from RMgmDB
P. falciparum 3D7
Refractory
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. falciparum 3D7 Asexual
Attenuated
https://www.biorxiv.org/content/10.1101/2020.02.13.947507v1.abstract (Knock down)
Late stage maturation affected. Haemoglobin motility reduced. Trolox rescues botth effects (to some extent)
Theo Sanderson, Francis Crick Institute
P. falciparum 3D7 Asexual
Attenuated
32601225 (Conditional)
modest merozoite invasion defect upon rupture of the PfPV5-null schizonts, reducing parasite replication
Abhinay Ramaprasad, The Francis Crick Institute

More information

PlasmoDB PKNH_0723800
GeneDB PKNH_0723800
Malaria Metabolic Pathways Localisation images
Pathways mapped to
Previous ID(s) PK9_2430w, PKH_072300
Orthologs PBANKA_0826700 , PCHAS_0827000 , PF3D7_0925900 , PVP01_0724400 , PVX_099710 , PY17X_0830000
Google Scholar Search for all mentions of this gene