Disruptability [+]

Species Disruptability Reference Submitter
P. berghei ANKA
Refractory
RMgm-4540 Imported from RMgmDB
P. falciparum 3D7
Refractory
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. falciparum 3D7 Asexual
Attenuated
https://www.biorxiv.org/content/10.1101/2020.02.13.947507v1.abstract (Knock down)
Late stage maturation affected. Haemoglobin motility reduced. Trolox rescues botth effects (to some extent)
Theo Sanderson, Francis Crick Institute
P. falciparum 3D7 Asexual
Attenuated
32601225 (Conditional)
modest merozoite invasion defect upon rupture of the PfPV5-null schizonts, reducing parasite replication
Abhinay Ramaprasad, The Francis Crick Institute

More information

PlasmoDB PBANKA_0826700
GeneDB PBANKA_0826700
Malaria Metabolic Pathways Localisation images
Pathways mapped to
Previous ID(s) PB000110.02.0, PBANKA_082670
Orthologs PCHAS_0827000 , PF3D7_0925900 , PKNH_0723800 , PVP01_0724400 , PVX_099710 , PY17X_0830000
Google Scholar Search for all mentions of this gene