Disruptability [+]

Species Disruptability Reference Submitter
P. berghei ANKA
Refractory
PlasmoGEM (Barseq) PlasmoGEM
P. falciparum 3D7
Refractory
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. falciparum 3D7 Asexual
Refractory
26067602 (Conditional) Theo Sanderson, Wellcome Trust Sanger Institute
P. falciparum 3D7 Asexual
Difference from wild-type
26067602 (Conditional) Theo Sanderson, Wellcome Trust Sanger Institute

Imaging data (from Malaria Metabolic Pathways)

Localisation of PF10_0328 during the IDC. Localisation of the tagged protein was visualised using anti-HA antibodies (red). Antibodies against GAPDH were used to visualise the cytosolic compartment. DAPI was used to visualise the nucleus. DIC images are shown as reference. The protein localized to unknown nuclear subcompartment.Oehring SC, Woodcroft BJ, Moes S, Wetzel J, Dietz O, Pulfer A, Dekiwadia C, Maeser P, Flueck C, Witmer K, Brancucci NM, Niederwieser I, Jenoe P, Ralph SA, Voss TS. Organellar proteomics reveals hundreds of novel nuclear proteins in the malaria parasite Plasmodium falciparum. Genome Biol. 2012 Nov 26;13(11):R108.

See original on MMP

Immunofluorescence detection of PfBDP1HA in the nucleus across the asexual life cycle of P. falciparum.Josling GA, Petter M, Oehring SC, Gupta AP, Dietz O, Wilson DW, Schubert T, Längst G, Gilson PR, Crabb BS, Moes S, Jenoe P, Lim SW, Brown GV, Bozdech Z, Voss TS, Duffy MF. A Plasmodium Falciparum Bromodomain Protein Regulates Invasion Gene Expression. Cell Host Microbe. 2015 17(6):741-51.

See original on MMP

More information

PlasmoDB PKNH_0618500
GeneDB PKNH_0618500
Malaria Metabolic Pathways Localisation images
Pathways mapped to
Previous ID(s) PK10_3440w, PKH_061810
Orthologs PBANKA_0517500 , PCHAS_0517600 , PF3D7_1033700 , PVP01_0618800 , PVX_111040 , PY17X_0518600
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