Disruptability [+]

Species Disruptability Reference Submitter
P. berghei ANKA
Refractory
PlasmoGEM (Barseq) PlasmoGEM

Mutant phenotypes [+]

None reported yet. Please press the '+' button above to add one.

Imaging data (from Malaria Metabolic Pathways)

Subcellular location of 14-3-3 in asexual blood stage parasites. Using anti-14-3-3I antibody in immunofluorescence assay, the Pf14-3-3I protein was localized in both nuclear and cytoplasmic compartments. This dual location is consistent with the pleiotropic role of 14-3-3 proteins that are involved in the regulation of subcellular localization, activation or inhibition of enzymes, and signal transduction.Dastidar EG, Dzeyk K, Krijgsveld J, Malmquist NA, Doerig C, Scherf A, Lopez-Rubio JJ. Comprehensive histone phosphorylation analysis and identification of pf14-3-3 protein as a histone H3 phosphorylation reader in malaria parasites. PLoS One. 2013;8(1):e53179.

See original on MMP

More information

PlasmoDB PKNH_0501800
GeneDB PKNH_0501800
Malaria Metabolic Pathways Localisation images
Pathways mapped to
Previous ID(s) PK8_1910w, PKH_051370
Orthologs PBANKA_0712600 , PCHAS_0721700 , PF3D7_0818200 , PVP01_0517100 , PVX_089505 , PY17X_0712800
Google Scholar Search for all mentions of this gene