Disruptability [+]

Species Disruptability Reference Submitter
P. falciparum 3D7
Possible
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen
P. berghei ANKA
Possible
RMgm-585 Imported from RMgmDB
P. chabaudi chabaudi
Possible
RMgm-4842 Imported from RMgmDB

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. berghei ANKA Asexual
No difference
RMgm-585 Imported from RMgmDB
P. berghei ANKA Asexual
Attenuated
PlasmoGEM (Barseq) PlasmoGEM
P. chabaudi chabaudi Asexual
Difference from wild-type
RMgm-4842
Transfected blood stages were selected in mice by pyrimethamine treatment
Imported from RMgmDB
P. berghei ANKA Gametocyte
No difference
RMgm-585 Imported from RMgmDB
P. berghei ANKA Ookinete
No difference
RMgm-585 Imported from RMgmDB
P. berghei ANKA Oocyst
Difference from wild-type
RMgm-585
Normal numbers of oocysts are produced. Inside oocysts morphologically normal sporozoites are formed. Sporozoites fail to egress from oocysts. No sporozoites are found in the salivary glands.
Imported from RMgmDB
P. berghei ANKA Sporozoite
Difference from wild-type
RMgm-585
Normal numbers of oocysts are produced. Inside oocysts morphologically normal sporozoites are formed. Sporozoites fail to egress from oocysts. No sporozoites are found in the salivary glands.Mechanically liberated sporozoites from oocysts show gliding motility and invade and infect hepatocytes but do not undergo further development.
Imported from RMgmDB
P. berghei ANKA Liver
Difference from wild-type
RMgm-585
Mechanically liberated sporozoites from oocysts show gliding motility and invade and infect hepatocytes in vitro but do not undergo further development.
Imported from RMgmDB

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