Last updated 10 months ago

Disruptability [+]

Species Disruptability Reference Submitter
P. chabaudi chabaudi
Possible
RMgm-4842 Imported from RMgmDB
P. berghei ANKA
Possible
RMgm-585 Imported from RMgmDB
P. falciparum 3D7
Possible
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. chabaudi chabaudi Asexual
Difference from wild-type
RMgm-4842
Transfected blood stages were selected in mice by pyrimethamine treatment
Imported from RMgmDB
P. berghei ANKA Asexual
No difference
RMgm-585 Imported from RMgmDB
P. berghei ANKA Asexual
Attenuated
PlasmoGEM (Barseq) PlasmoGEM
P. berghei ANKA Gametocyte
No difference
RMgm-585 Imported from RMgmDB
P. berghei ANKA Ookinete
No difference
RMgm-585 Imported from RMgmDB
P. berghei ANKA Oocyst
Difference from wild-type
RMgm-585
Normal numbers of oocysts are produced. Inside oocysts morphologically normal sporozoites are formed. Sporozoites fail to egress from oocysts. No sporozoites are found in the salivary glands.
Imported from RMgmDB
P. berghei ANKA Sporozoite
Difference from wild-type
RMgm-585
Normal numbers of oocysts are produced. Inside oocysts morphologically normal sporozoites are formed. Sporozoites fail to egress from oocysts. No sporozoites are found in the salivary glands.Mechanically liberated sporozoites from oocysts show gliding motility and invade and infect hepatocytes but do not undergo further development.
Imported from RMgmDB
P. berghei ANKA Liver
Difference from wild-type
RMgm-585
Mechanically liberated sporozoites from oocysts show gliding motility and invade and infect hepatocytes in vitro but do not undergo further development.
Imported from RMgmDB

More information

PlasmoDB PCHAS_1304000
GeneDB PCHAS_1304000
Malaria Metabolic Pathways Localisation images
Pathways mapped to
Previous ID(s) PC000328.01.0, PC000344.01.0, PC000555.01.0, PC000820.00.0, PC300258.00.0, PC301286.00.0, PC301724.00.0, PC302050.00.0, PCAS_130400, PCHAS_130400
Orthologs PBANKA_1300800 , PF3D7_1475400 , PKNH_1245700 , PVP01_1270300 , PVX_118648 , PY17X_1304400
Google Scholar Search for all mentions of this gene