| Species | Disruptability | Reference | Submitter | |
|---|---|---|---|---|
| P. falciparum 3D7 |
Possible |
USF piggyBac screen (Insert. mut.) | USF PiggyBac Screen | |
| P. falciparum 3D7 |
Refractory |
35404116 Eight KO attempts failed |
Theo Sanderson, Francis Crick Institute | |
| P. berghei ANKA |
Possible |
RMgm-1369 | Imported from RMgmDB | |
| P. berghei ANKA |
Possible |
PlasmoGEM (Barseq) | PlasmoGEM | |
| P. berghei ANKA |
Possible |
RMgm-4342 | Imported from RMgmDB | |
| Species | Stage | Phenotype | Reference | Submitter |
|---|---|---|---|---|
| P. falciparum 3D7 | Asexual |
No difference |
35404116 (Knock down)
No difference noted with partial knockdown |
Theo Sanderson, Francis Crick Institute |
| P. berghei ANKA | Asexual |
Difference from wild-type |
RMgm-1369
Reduced parasite multiplication rate (PMR): 55% |
Imported from RMgmDB |
| P. berghei ANKA | Asexual |
Attenuated |
PlasmoGEM (Barseq) | PlasmoGEM |
| P. berghei ANKA | Asexual |
Difference from wild-type |
RMgm-4342
Not essential for blood stage growth/multiplication |
Imported from RMgmDB |
| P. berghei ANKA | Gametocyte |
Difference from wild-type |
RMgm-1369
Strongly reduced exflagellation |
Imported from RMgmDB |
| P. berghei ANKA | Sporozoite |
No difference |
RMgm-1369 | Imported from RMgmDB |
| P. berghei ANKA | Liver |
Difference from wild-type |
RMgm-1369
No transmission by bite of infected mosquitoes; except an occasional breakthrough infection, normal liver-stage parasite numbers and size in vitro but with distorted nuclei |
Imported from RMgmDB |
| PlasmoDB | PF3D7_1440800 |
| GeneDB | PF3D7_1440800 |
| Malaria Metabolic Pathways | Localisation images Pathways mapped to |
| Previous ID(s) | PF14_0387 |
| Orthologs | PBANKA_1304700 , PCHAS_1307900 , PKNH_1241500 , PVP01_1266200 , PVX_118450 , PY17X_1308500 |
| Google Scholar | Search for all mentions of this gene |