Last updated 2 years ago

Disruptability [+]

Species Disruptability Reference Submitter
P. falciparum 3D7
Possible
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen
P. berghei ANKA
Possible
RMgm-1271 Imported from RMgmDB
P. berghei ANKA
Possible
RMgm-1270 Imported from RMgmDB

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. falciparum 3D7 Asexual
Attenuated
24453970 (Conditional)
\" To investigate its importance in P. falciparum, we generated a pepc null mutant (D10(Δpepc) ), which was only achievable when malate, a reduction product of oxaloacetate, was added to the growth medium. D10(Δpepc) had a severe growth defect in vitro, which was partially reversed by addition of malate or fumarate, suggesting that pepc may be essential in vivo. \"
Theo Sanderson, Francis Crick Institute
P. berghei ANKA Asexual
Difference from wild-type
RMgm-1271
Reduced growth/multiplication of asexual blood stages
Imported from RMgmDB
P. berghei ANKA Asexual
Difference from wild-type
RMgm-1270
Reduced growth/multiplication of asexual blood stages
Imported from RMgmDB
P. berghei ANKA Gametocyte
Difference from wild-type
RMgm-1271
Reduced gametocyte production
Imported from RMgmDB
P. berghei ANKA Gametocyte
Difference from wild-type
RMgm-1270
Reduced gametocyte production
Imported from RMgmDB
P. berghei ANKA Ookinete
Difference from wild-type
RMgm-1270
Strongly reduced ookinete formation
Imported from RMgmDB
P. berghei ANKA Ookinete
Difference from wild-type
RMgm-1271
Strongly reduced ookinete formation
Imported from RMgmDB
P. berghei ANKA Oocyst
Difference from wild-type
RMgm-1270
Strongly reduced oocyst formation
Imported from RMgmDB
P. berghei ANKA Oocyst
Difference from wild-type
RMgm-1271
Strongly reduced oocyst formation
Imported from RMgmDB
P. berghei ANKA Sporozoite
Difference from wild-type
RMgm-1270
No sporozoite formation
Imported from RMgmDB
P. berghei ANKA Sporozoite
Difference from wild-type
RMgm-1271
No sporozoite formation
Imported from RMgmDB

More information