Disruptability [+]

Species Disruptability Reference Submitter
P. falciparum 3D7
Refractory
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen
P. berghei ANKA
Refractory
PlasmoGEM (Barseq) PlasmoGEM

Mutant phenotypes [+]

None reported yet. Please press the '+' button above to add one.

Imaging data (from Malaria Metabolic Pathways)

Comparison of PfSec12 localization with markers for the ER and Golgi. Parasites were cotransfected with plasmids for expression of mRFP-PfSec12 (from the native pfsec12 5′ UTR) with either (A) GFP-SDEL, a marker for the general ER, or (B) PfGRASP-GFP, a cis-Golgi marker. mRFP-PfSec12 was localized throughout the ER coincident with GFP-SDEL, in close apposition to PfGRASP-labelled Golgi. Bar = 5 μm.Lee MC, Moura PA, Miller EA, Fidock DA. Plasmodium falciparum Sec24 marks transitional ER that exports a model cargo via a diacidic motif. Mol Microbiol. 2008 68(6):1535-46.

See original on MMP

More information

PlasmoDB PF3D7_1322000
GeneDB PF3D7_1322000
Malaria Metabolic Pathways Localisation images
Pathways mapped to
Previous ID(s) MAL13P1.121
Orthologs PBANKA_1337400 , PCHAS_1342000 , PKNH_1206800 , PVP01_1232600 , PVX_116770 , PY17X_1342100
Google Scholar Search for all mentions of this gene