Disruptability [+]

Species Disruptability Reference Submitter
P. berghei ANKA
Refractory
PlasmoGEM (Barseq) PlasmoGEM
P. falciparum 3D7
Refractory
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen

Mutant phenotypes [+]

None reported yet. Please press the '+' button above to add one.

Imaging data (from Malaria Metabolic Pathways)

Comparison of PfSec12 localization with markers for the ER and Golgi. Parasites were cotransfected with plasmids for expression of mRFP-PfSec12 (from the native pfsec12 5′ UTR) with either (A) GFP-SDEL, a marker for the general ER, or (B) PfGRASP-GFP, a cis-Golgi marker. mRFP-PfSec12 was localized throughout the ER coincident with GFP-SDEL, in close apposition to PfGRASP-labelled Golgi. Bar = 5 μm.Lee MC, Moura PA, Miller EA, Fidock DA. Plasmodium falciparum Sec24 marks transitional ER that exports a model cargo via a diacidic motif. Mol Microbiol. 2008 68(6):1535-46.

See original on MMP

More information

PlasmoDB PBANKA_1337400
GeneDB PBANKA_1337400
Malaria Metabolic Pathways Localisation images
Pathways mapped to
Previous ID(s) PB000368.00.0, PB000842.01.0, PBANKA_133740
Orthologs PCHAS_1342000 , PF3D7_1322000 , PKNH_1206800 , PVP01_1232600 , PVX_116770 , PY17X_1342100
Google Scholar Search for all mentions of this gene