| Species | Disruptability | Reference | Submitter | |
|---|---|---|---|---|
| P. falciparum 3D7 |
Possible |
USF piggyBac screen (Insert. mut.) | USF PiggyBac Screen | |
| P. berghei ANKA |
Possible |
RMgm-1289 | Imported from RMgmDB | |
| P. berghei ANKA |
Possible |
RMgm-1127 | Imported from RMgmDB | |
| P. berghei ANKA |
Possible |
PlasmoGEM (Barseq) | PlasmoGEM | |
| Species | Stage | Phenotype | Reference | Submitter |
|---|---|---|---|---|
| P. berghei ANKA | Asexual |
No difference |
RMgm-1289 | Imported from RMgmDB |
| P. berghei ANKA | Asexual |
No difference |
RMgm-1127 | Imported from RMgmDB |
| P. berghei ANKA | Asexual |
No difference |
PlasmoGEM (Barseq) | PlasmoGEM |
| P. berghei ANKA | Gametocyte |
No difference |
RMgm-1289 | Imported from RMgmDB |
| P. berghei ANKA | Gametocyte |
Difference from wild-type |
RMgm-1127
Normal numbers of gametocytes. Exflagellation numbers are formed. Activated pbgamer male gametocytes produce morphologically normal and motile microgametes; however, the vast majority of them was unable to detach from the residual body of the gametocytes and remained attached to the exflagellation centers even 30 min post activation. |
Imported from RMgmDB |
| P. berghei ANKA | Ookinete |
Difference from wild-type |
RMgm-1289
The mutants developed into ookinetes with normal conversion rates. However, the morphology of ookinetes appeared somewhat laterally longer than those of the wild-type parasites. Calculation of the heightwidth ratios of these ookinetes confirmed that they had abnormal morphologies. |
Imported from RMgmDB |
| P. berghei ANKA | Ookinete |
Difference from wild-type |
RMgm-1127
(Strongly) reduced ookinete formation (18% compared to 72% in wild type) |
Imported from RMgmDB |
| P. berghei ANKA | Oocyst |
Difference from wild-type |
RMgm-1289
Strongly reduced oocyst production. |
Imported from RMgmDB |
| P. berghei ANKA | Oocyst |
Difference from wild-type |
RMgm-1127
(Strongly) reduced ookinete formation (18% compared to 72% in wild type). (Strongly) reduced oocyst formation. |
Imported from RMgmDB |
| P. berghei ANKA | Sporozoite |
Difference from wild-type |
RMgm-1289
Strongly reduced sporozoite production. |
Imported from RMgmDB |
| P. berghei ANKA | Sporozoite |
Difference from wild-type |
RMgm-1127
(Strongly) reduced oocyst formation. (Strongly) reduced sporozoite formation. |
Imported from RMgmDB |
| P. berghei ANKA | Liver |
Difference from wild-type |
RMgm-1127
(Strongly) reduced sporozoite formation. However, sporozoites are infectious to mice (by mosquito-bite infection) |
Imported from RMgmDB |
| PlasmoDB | PF3D7_0805200 |
| GeneDB | PF3D7_0805200 |
| Malaria Metabolic Pathways | Localisation images Pathways mapped to |
| Previous ID(s) | PF08_0119 |
| Orthologs | PBANKA_1225400 , PCHAS_1226000 , PKNH_0114000 , PVP01_0115300 , PVX_093500 , PY17X_1228600 |
| Google Scholar | Search for all mentions of this gene |