|P. falciparum 3D7||Asexual||
| 34750454 (Conditional)
Di-Cre based deletion. \'Deletion resulted in a significant reduction of parasite growth in vitro, reduced ubiquitylation of the Lys63 residue of ubiquitin attached to protein substrates, and an increased sensitivity of the parasite to both the mutagen, methyl methanesulfonate and the antimalarial drug dihydroartemisinin (DHA), but not chloroquine.\'
|Theo Sanderson, Francis Crick Institute|