Last updated 10 months ago

Disruptability [+]

Species Disruptability Reference Submitter
P. chabaudi chabaudi
Possible
RMgm-4839 Imported from RMgmDB
P. berghei ANKA
Possible
PlasmoGEM (Barseq) PlasmoGEM
P. berghei ANKA
Possible
http://plasmodb.org/plasmo/showComment.do?projectId=PlasmoDB&stableId=PF3D7_1215900&commentTargetId=gene#21500 Theo Sanderson, Wellcome Trust Sanger Institute
P. falciparum 3D7
Possible
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen
P. yoelii yoelii 17X
Possible
RMgm-4758 Imported from RMgmDB
P. yoelii yoelii 17X
Possible
RMgm-4838 Imported from RMgmDB

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. berghei ANKA Asexual
Attenuated
http://plasmodb.org/plasmo/showComment.do?projectId=PlasmoDB&stableId=PF3D7_1215900&commentTargetId=gene#21500 Theo Sanderson, Wellcome Trust Sanger Institute
P. yoelii yoelii 17X Asexual
No difference
RMgm-4758 Imported from RMgmDB
P. yoelii yoelii 17X Asexual
Difference from wild-type
RMgm-4838
The proportion of parasites at early trophozoite stage displayed weak daily rhythmicity in both the wild type and sr10KO clone (amplitude for P. yoelii wild type: 0.30 0.02 and P. yoelii sr10KO: 0.31 0.01), yet the intra-erythrocytic developmental cycle (IDC) duration was shorter in the sr10KO clone (sr10KO IDC duration 24.45 h; wild type IDC duration ~28 h).
Imported from RMgmDB
P. yoelii yoelii 17X Gametocyte
Difference from wild-type
RMgm-4758
(somewhat) higher production of gametocytes; (somewhat) lower exflagellation
Imported from RMgmDB

More information

PlasmoDB PCHAS_1433600
GeneDB PCHAS_1433600
Malaria Metabolic Pathways Localisation images
Pathways mapped to
Previous ID(s) PC300772.00.0, PC301896.00.0, PCAS_143360, PCHAS_143360
Orthologs PBANKA_1431600 , PF3D7_1215900 , PKNH_1435400 , PVP01_1434700 , PVX_123475 , PY17X_1433900
Google Scholar Search for all mentions of this gene