Disruptability [+]

Species Disruptability Reference Submitter
P. berghei ANKA
Possible
PlasmoGEM (Barseq) PlasmoGEM
P. falciparum 3D7
Possible
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen
P. yoelii yoelii 17X
Possible
RMgm-4779 Imported from RMgmDB

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. berghei ANKA Asexual
No difference
PlasmoGEM (Barseq) PlasmoGEM
P. yoelii yoelii 17X Asexual
No difference
RMgm-4779 Imported from RMgmDB
P. yoelii yoelii 17X Gametocyte
Difference from wild-type
RMgm-4779
normal production of gametocytes; normal exflagellation
Imported from RMgmDB

Imaging data (from Malaria Metabolic Pathways)

Immunofluorescence microscopy of the intracellular distribution of PFGCN20 in P. falciparum (FAC8) infected erythrocytes. Smears of erythrocytic cultures were fixed, permeabilized and probed with AF43 at a dilution of 1:100. Bound AF43 were visualized with anti-rabbit IgG-FITC secondary antibodies. A: Red blood cell infected by single ring-stage parasite. B: Red blood cell infected with three ring-stage parasites. C: Late ring stage. D, E: Trophozoite to early schizont stages. F: Late schizont stage. Bar corresponds to 2.5 mm.Bozdech Z, VanWye J, Haldar K, Schurr E. The human malaria parasite Plasmodium falciparum exports the ATP-binding cassette protein PFGCN20 to membrane structures in the host red blood cell. Mol Biochem Parasitol. 1998 97:81-95. Copyright Elsevier 2009.

See original on MMP

More information

PlasmoDB PBANKA_0926600
GeneDB PBANKA_0926600
Malaria Metabolic Pathways Localisation images
Pathways mapped to
Previous ID(s) PB000364.03.0, PB000693.01.0, PBANKA_092660
Orthologs PCHAS_0917700 , PF3D7_1121700 , PKNH_0919400 , PVP01_0922300 , PVX_091705 , PY17X_0928600
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