Disruptability [+]

Species Disruptability Reference Submitter
P. berghei ANKA
Possible
RMgm-220 Imported from RMgmDB

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. berghei ANKA Asexual
No difference
RMgm-220 Imported from RMgmDB
P. berghei ANKA Gametocyte
No difference
RMgm-220 Imported from RMgmDB
P. berghei ANKA Ookinete
No difference
RMgm-220 Imported from RMgmDB
P. berghei ANKA Oocyst
No difference
RMgm-220 Imported from RMgmDB
P. berghei ANKA Sporozoite
Difference from wild-type
RMgm-220
Normal numbers of oocysts are produced. The number of midgut sporozoites per mosquito was comparable to wild type. Only a few sporozoites were found to be associated with the salivary glands. Conversely, the number of hemolymph sporozoites significantly increased, indicating that they were normally released from the oocysts but accumulated in the hemolymph as a result of the lack of sporozoite entry into the salivary gland.Midgut sporozoites showed normal gliding motility. Mutant midgut sporozoites showed an infectivity to rats comparable to wild type midgut sporozoites.
Imported from RMgmDB
P. berghei ANKA Liver
Difference from wild-type
RMgm-220
Mutant midgut sporozoites showed an infectivity to rats comparable to wild type midgut sporozoites as shown by infection rates and prepatent period in rats after intravenous injection of sporozoites.
Imported from RMgmDB

More information

PlasmoDB PBANKA_0901300
GeneDB PBANKA_0901300
Malaria Metabolic Pathways Localisation images
Pathways mapped to
Previous ID(s) PB000798.02.0, PBANKA_090130, PBANKA_0901300.1, PBANKA_0901300.2, PbMAEBL
Orthologs PCHAS_0702500 , PF3D7_1147800 , PF3D7_1147800 , PKNH_0945700 , PVP01_0948400 , PVX_092975
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