PY17X_1433900 serpentine receptor, putative (SR10)

Last updated 4 years ago

Disruptability [+]

Species Disruptability Reference Submitter
P. yoelii yoelii 17X
Possible		 RMgm-4758 Imported from RMgmDB
P. yoelii yoelii 17X
Possible		 RMgm-4838 Imported from RMgmDB
P. berghei ANKA
Possible		 PlasmoGEM (Barseq) PlasmoGEM
P. berghei ANKA
Possible		 http://plasmodb.org/plasmo/showComment.do?projectId=PlasmoDB&stableId=PF3D7_1215900&commentTargetId=gene#21500 Theo Sanderson, Wellcome Trust Sanger Institute
P. chabaudi chabaudi
Possible		 RMgm-4839 Imported from RMgmDB
P. falciparum 3D7
Possible		 USF piggyBac screen (Insert. mut.) USF PiggyBac Screen
P. falciparum 3D7
Possible		 32890576
\"Gene disruption of SR10 leads to impaired intraerythrocytic replication and strongly reduces gametocyte numbers. \"
 Theo Sanderson, Francis Crick Institute

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. yoelii yoelii 17X Asexual
No difference		 RMgm-4758 Imported from RMgmDB
P. yoelii yoelii 17X Asexual
Difference from wild-type		 RMgm-4838
The proportion of parasites at early trophozoite stage displayed weak daily rhythmicity in both the wild type and sr10KO clone (amplitude for P. yoelii wild type: 0.30 0.02 and P. yoelii sr10KO: 0.31 0.01), yet the intra-erythrocytic developmental cycle (IDC) duration was shorter in the sr10KO clone (sr10KO IDC duration 24.45 h; wild type IDC duration ~28 h).
 Imported from RMgmDB
P. yoelii yoelii 17X Gametocyte
Difference from wild-type		 RMgm-4758
(somewhat) higher production of gametocytes; (somewhat) lower exflagellation
 Imported from RMgmDB
P. berghei ANKA Asexual
Attenuated		 http://plasmodb.org/plasmo/showComment.do?projectId=PlasmoDB&stableId=PF3D7_1215900&commentTargetId=gene#21500 Theo Sanderson, Wellcome Trust Sanger Institute
P. falciparum 3D7 Asexual
Attenuated		 32890576
\"Gene disruption of SR10 leads to impaired intraerythrocytic replication and strongly reduces gametocyte numbers. \"
 Theo Sanderson, Francis Crick Institute
P. falciparum 3D7 Gametocyte
Attenuated		 32890576
\"Gene disruption of SR10 leads to impaired intraerythrocytic replication and strongly reduces gametocyte numbers. \"
 Theo Sanderson, Francis Crick Institute

More information

PlasmoDB PY17X_1433900
GeneDB PY17X_1433900
Malaria Metabolic Pathways Localisation images
Pathways mapped to
Previous ID(s) null
Orthologs PBANKA_1431600 , PCHAS_1433600 , PF3D7_1215900 , PKNH_1435400 , PVP01_1434700 , PVX_123475
Google Scholar Search for all mentions of this gene