Disruptability [+]

Species Disruptability Reference Submitter
P. berghei ANKA
Possible
RMgm-101 Imported from RMgmDB
P. berghei ANKA
Possible
PlasmoGEM (Barseq) PlasmoGEM
P. falciparum 3D7
Possible
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. berghei ANKA Asexual
No difference
RMgm-101 Imported from RMgmDB
P. berghei ANKA Asexual
No difference
PlasmoGEM (Barseq) PlasmoGEM
P. berghei ANKA Gametocyte
No difference
RMgm-101 Imported from RMgmDB
P. berghei ANKA Ookinete
No difference
RMgm-101 Imported from RMgmDB
P. berghei ANKA Oocyst
Difference from wild-type
RMgm-101
Normal' numbers of oocysts are produced: 149% of wild type (79-209%). Sporozoite formation (sporulation) is strongly affected in the 'mature' oocysts. Most oocysts appear either immature/enlarged or degenerate/vacuolated.
Imported from RMgmDB
P. berghei ANKA Sporozoite
Difference from wild-type
RMgm-101
Low numbers of sporozoites are produced: 8.7% of wild type (1.6-19.6). No tramission to C57BL/6 mice by mosquito bite
Imported from RMgmDB

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