Disruptability [+]

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Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. falciparum 3D7 Asexual
Attenuated
32273345 (Knock down)
"As shown in Figure 4B, knocking down PfmtRPS17 caused a severe growth arrest. Although the parasite appeared morphologically healthy under a light microscope after aTc had been removed for 1 IDC, detrimental changes were observed after 2 IDCs without aTc (Supplementary Figure 4B). After aTc removal for 3 IDCs or longer, D10-PfmtRPS17-3HA parasites were severely deteriorated."
Theo Sanderson, Francis Crick Institute

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