Disruptability [+]

Species Disruptability Reference Submitter
P. yoelii yoelii 17X
Possible
RMgm-5093 Imported from RMgmDB
P. falciparum 3D7
Possible
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. yoelii yoelii 17X Asexual
Difference from wild-type
RMgm-5093
No significant asexual blood-stage growth defects were observed for py17x_0945600-null parasites until late in the blood-stage infection (day 10). At this point, there was a small but statistically significant decrease in peak parasitemia with a concomitant earlier time to parasite clearance
Imported from RMgmDB
P. yoelii yoelii 17X Gametocyte
Difference from wild-type
RMgm-5093
Evidence is presented for a slight increase in gametocyte production; no male gamete production (exflagellation); female gametes infertile (i.e. were unable to produce developing zygotes)
Imported from RMgmDB
P. yoelii yoelii 17X Ookinete
Difference from wild-type
RMgm-5093
No ookinete or oocyst production
Imported from RMgmDB
P. yoelii yoelii 17X Oocyst
Difference from wild-type
RMgm-5093
No ookinete or oocyst production
Imported from RMgmDB

More information