| Species | Disruptability | Reference | Submitter | |
|---|---|---|---|---|
| P. yoelii yoelii 17X |
Possible |
RMgm-5050 | Imported from RMgmDB | |
| P. berghei ANKA |
Possible |
RMgm-123 | Imported from RMgmDB | |
| P. falciparum 3D7 |
Refractory |
USF piggyBac screen (Insert. mut.) | USF PiggyBac Screen | |
| Species | Stage | Phenotype | Reference | Submitter |
|---|---|---|---|---|
| P. yoelii yoelii 17X | Ookinete |
Difference from wild-type |
RMgm-5050
Ookinetes are formed but no traversal through mosquito midgut cells |
Imported from RMgmDB |
| P. yoelii yoelii 17X | Oocyst |
Difference from wild-type |
RMgm-5050
Ookinetes are formed but no traversal through mosquito midgut cells |
Imported from RMgmDB |
| P. berghei ANKA | Asexual |
No difference |
RMgm-123 | Imported from RMgmDB |
| P. berghei ANKA | Gametocyte |
No difference |
RMgm-123 | Imported from RMgmDB |
| P. berghei ANKA | Ookinete |
Difference from wild-type |
RMgm-123
Normal numbers of ookinetes are produced. Most (>99%) of the ookinetes do not develop into oocysts. Ookinetes also failed to infect mosquitoes when ookinetes were cultured in vitro and fed to mosquitoes via membrane feeding. |
Imported from RMgmDB |
| P. berghei ANKA | Oocyst |
Difference from wild-type |
RMgm-123
No or very few oocysts are formed. Most (>99%) of the ookinetes do not develop into oocysts. However, the block in infection was not absolute, since a single oocyst was observed in two of 50 dissected mosquitoes in one experiment. Moreover, in another experiment a single sporozoite was observed in salivary gland dissections. |
Imported from RMgmDB |
| P. berghei ANKA | Sporozoite |
Difference from wild-type |
RMgm-123
No or very few oocysts are formed. Most (>99%) of the ookinetes do not develop into oocysts. However, the block in infection was not absolute, since a single oocyst was observed in two of 50 dissected mosquitoes in one experiment. Moreover, in another experiment a single sporozoite was observed in salivary gland dissections.Despite the low numbers of sporozoites, infected mosquitoes were able to transmit parasites to C57BL/6 mice. |
Imported from RMgmDB |
| P. berghei ANKA | Liver |
No difference |
RMgm-123 | Imported from RMgmDB |
| PlasmoDB | PY17X_0711800 |
| GeneDB | PY17X_0711800 |
| Malaria Metabolic Pathways | Localisation images Pathways mapped to |
| Previous ID(s) | null |
| Orthologs | PBANKA_0711600 , PCHAS_0720700 , PF3D7_0819200 , PKNH_1313000 , PVP01_0515100 , PVX_089405 |
| Google Scholar | Search for all mentions of this gene |