Last updated 4 years ago

Disruptability [+]

Species Disruptability Reference Submitter
P. yoelii yoelii 17X
Possible
RMgm-4818 Imported from RMgmDB
P. berghei ANKA
Possible
RMgm-4155 Imported from RMgmDB
P. berghei ANKA
Possible
RMgm-12 Imported from RMgmDB
P. berghei ANKA
Possible
PlasmoGEM (Barseq) PlasmoGEM
P. berghei ANKA
Possible
RMgm-4155 Imported from RMgmDB
P. berghei ANKA
Possible
RMgm-4546 Imported from RMgmDB
P. falciparum 3D7
Possible
20466936 (Conditional) Theo Sanderson, Wellcome Trust Sanger Institute
P. falciparum 3D7
Possible
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. yoelii yoelii 17X Asexual
No difference
RMgm-4818 Imported from RMgmDB
P. yoelii yoelii 17X Gametocyte
Difference from wild-type
RMgm-4818
Normal gametocyte production; fertile female gametes are formed; no formation of male gametes
Imported from RMgmDB
P. berghei ANKA Asexual
No difference
RMgm-4155 Imported from RMgmDB
P. berghei ANKA Asexual
No difference
RMgm-12 Imported from RMgmDB
P. berghei ANKA Asexual
Attenuated
PlasmoGEM (Barseq) PlasmoGEM
P. berghei ANKA Asexual
No difference
RMgm-4155 Imported from RMgmDB
P. falciparum 3D7 Asexual
No difference
20466936 (Conditional) Theo Sanderson, Wellcome Trust Sanger Institute
P. berghei ANKA Gametocyte
Difference from wild-type
RMgm-4155
No male gametes are formed after activation of male gametocytes.
Imported from RMgmDB
P. berghei ANKA Gametocyte
Difference from wild-type
RMgm-12
No male gametes are formed; Male gametocytes are not affected in the ability to 'round up'and lyse the host cell; in male gametocytes axoneme formation, formation of mitotic spindles and DNA synthesis is inhibited/blocked.Female gametes are fertile; mutant female gametes fertilised by wild type male gametes produce ookinetes. However, these ookinetes are strongly affected in their ability to produce oocysts
Imported from RMgmDB
P. berghei ANKA Gametocyte
Difference from wild-type
RMgm-4155
No male gametes are formed after activation of male gametocytes.
Imported from RMgmDB
P. berghei ANKA Ookinete
Difference from wild-type
RMgm-4155
No male gametes are formed after activation of male gametocytes (no exflagellation).
Imported from RMgmDB
P. berghei ANKA Ookinete
Difference from wild-type
RMgm-12
See the description of the phenotype of Gametocytes/Gametes and Additional remarks phenotype
Imported from RMgmDB
P. berghei ANKA Ookinete
Difference from wild-type
RMgm-4155
No male gametes are formed after activation of male gametocytes (no exflagellation).
Imported from RMgmDB
P. berghei ANKA Oocyst
Difference from wild-type
RMgm-12
See the description of the phenotype of Gametocytes/Gametes and 'Additional remarks phenotype'.
Imported from RMgmDB

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