Species | Disruptability | Reference | Submitter | |
---|---|---|---|---|
P. falciparum 3D7 |
Refractory |
USF piggyBac screen (Insert. mut.) | USF PiggyBac Screen |
Localization of epitope-tagged ATP synthase subunits detected using immuno-fluoresence microscopy. Immunofluoresence of alpha, gamma, delta, epsilon, OSCP and c subunits expressed under control of the mRPL2 promoter. Expression of the beta subunit was under the control of its own promoter. Green fluorescence: Anti-HA antibody (AlexaFluor 488-conjugated secondary antibody). Red fluorescence: Mitotracker Red CM-H2XRos. Blue fluorescence: DAPI (4'-6-Diamidino-2-phenylindole). DIC: Differential interference contrast microscopy.Balabaskaran Nina P, Morrisey JM, Ganesan SM, Ke H, Pershing AM, Mather MW, Vaidya AB. ATP synthase complex of Plasmodium falciparum: dimeric assembly in mitochondrial membranes and resistance to genetic disruption. J Biol Chem. 2011 286(48):41312-22. PMID:
See original on MMPPlasmoDB | PVX_122330 |
GeneDB | PVX_122330 |
Malaria Metabolic Pathways | Localisation images Pathways mapped to |
Previous ID(s) | Pv122330 |
Orthologs | PBANKA_1408500 , PCHAS_1410400 , PF3D7_1310000 , PKNH_1410400 , PVP01_1411000 , PY17X_1410300 |
Google Scholar | Search for all mentions of this gene |