Immunolocalization of a putative P. falciparum copper transport protein. Asexual P. falciparum parasites were grown in vitro, synchronized by sorbitol treatment and samples removed at five time points (A – E). Fixed parasites were probed with chicken antipeptide antibodies targeting PF14_0369 and rabbit antibodies against Exp-1. Chicken antibodies were detected with a Cy3-conjugated antibody and rabbit antibodies with a Cy2-conjugated antibody. Panels are representative of the following stages of asexual parasite development: A. early rings; B. late rings; C. early trophozoites; D. late trophozoites; E. schizonts. Parasite DNA was stained with Hoechst. Scale bar is 5 μm.Choveaux DL, Przyborski JM, Goldring JD. A Plasmodium falciparum copper-binding membrane protein with copper transport motifs. Malar J. 2012 11(1):397.

Subcellular distribution of proteins predicted to be involved in invasion. All proteins were localized in schizonts (s) and free merozoites (m) using GFP-fusion proteins and grouped according to their predominant GFP localization. Shown are proteins that revealed cytosolic (PFC0945w, PFI1565w’PF11_0190 and PFL2100w, apicoplast (PFE0145w), mitochondrial and other subcellular distribution but may be involved in invasion.Hu G, Cabrera A, Kono M, Mok S, Chaal BK, Haase S, Engelberg K, Cheemadan S, Spielmann T, Preiser PR, Gilberger TW, Bozdech Z. Transcriptional profiling of growth perturbations of the human malaria parasite Plasmodium falciparum. Nat Biotechnol. 2010 28(1):91-8.