Disruptability [+]

Species Disruptability Reference Submitter
P. berghei ANKA
Possible
RMgm-108 Imported from RMgmDB
P. berghei ANKA
Possible
PlasmoGEM (Barseq) PlasmoGEM
P. falciparum 3D7
Possible
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. berghei ANKA Asexual
No difference
RMgm-108 Imported from RMgmDB
P. berghei ANKA Gametocyte
No difference
RMgm-108 Imported from RMgmDB
P. berghei ANKA Ookinete
No difference
RMgm-108 Imported from RMgmDB
P. berghei ANKA Oocyst
Difference from wild-type
RMgm-108
Oocyst numbers in A. stephensi were comparable to wild type (ranging from 150250 oocysts per mosquito). Sporozoite formation blocked inside the oocysts. No sporozoite formation was detectable within the oocysts by either fluorescence or phase-contrast microscopy.
Imported from RMgmDB
P. berghei ANKA Sporozoite
Difference from wild-type
RMgm-108
Sporozoite formation blocked inside the oocysts. No sporozoite formation was detectable within the oocysts by either fluorescence or phase-contrast microscopy. No sporozoites in salivary glands. No blood stage infection in C57BL/6 mice after feeding of infected mosquitoes on these mice.
Imported from RMgmDB

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