Species | Disruptability | Reference | Submitter | |
---|---|---|---|---|
P. berghei ANKA |
Possible |
RMgm-301 | Imported from RMgmDB | |
P. yoelii yoelii 17X |
Possible |
RMgm-5288 | Imported from RMgmDB |
Species | Stage | Phenotype | Reference | Submitter |
---|---|---|---|---|
P. berghei ANKA | Asexual |
No difference |
RMgm-301 | Imported from RMgmDB |
P. yoelii yoelii 17X | Asexual |
No difference |
RMgm-5288 | Imported from RMgmDB |
P. berghei ANKA | Gametocyte |
No difference |
RMgm-301 | Imported from RMgmDB |
P. yoelii yoelii 17X | Gametocyte |
No difference |
RMgm-5288 | Imported from RMgmDB |
P. berghei ANKA | Ookinete |
No difference |
RMgm-301 | Imported from RMgmDB |
P. yoelii yoelii 17X | Ookinete |
Difference from wild-type |
RMgm-5288
The aprp2 mutant showed normal asexual blood stage proliferation and gametocyte production. However, the mutant displayed a moderate decrease in mature ookinete formation. The mature-looking mutant ookinetes lost the crescent shape and had an impaired gliding ability compared to the WT. As a consequence, the aprp2 mutant produced significantly decreased numbers of midgut oocysts in the infected mosquitoes. These defects caused by depletion of either APRp2 were in concordance with the phenotype of the apr2 mutant. |
Imported from RMgmDB |
P. yoelii yoelii 17X | Oocyst |
Difference from wild-type |
RMgm-5288
The mutant displayed a moderate decrease in mature ookinete formation. The mature-looking mutant ookinetes lost the crescent shape and had an impaired gliding ability compared to the WT. As a consequence, the aprp2 mutant produced significantly decreased numbers of midgut oocysts in the infected mosquitoes. These defects caused by depletion of either APRp2 were in concordance with the phenotype of the apr2 mutant. |
Imported from RMgmDB |
PlasmoDB | PVX_117735 |
GeneDB | PVX_117735 |
Malaria Metabolic Pathways | Localisation images Pathways mapped to |
Previous ID(s) | Pv117735 |
Orthologs | PBANKA_1318600 , PCHAS_1321900 , PF3D7_1454900 , PKNH_1227200 , PVP01_1252100 , PY17X_1322400 |
Google Scholar | Search for all mentions of this gene |