Upper panel: Co-localization of PfTudor-SN and Histone h2A. Immunofluorescence assays were performed at P. falciparum schizont stage using peptide antibodies generated against Histone h2A. The interacting h2A in the parasite were co-localized with anti-PfTudor-SN antibody in the nucleus.Lower panel: .Co-localization of PfTudor-SN and SmD1 protein of the parasite. PfTudor-SN was also co-localized with the PfSmD1 suggesting a close association between themHossain MJ, Korde R, Singh PK, Kanodia S, Ranjan R, Ram G, Kalsey GS, Singh R, Malhotra P. Plasmodium falciparum Tudor Staphylococcal Nuclease interacting proteins suggest its role in nuclear as well as splicing processes. Gene. 2010 468:48-57. Copyright Elsevier 2011

Co-localization of PfTudor-SN and histone H2A. The interacting proteins in the parasite were co-localized with anti-PfTudor-SN antibody. FITC and Cy3 labeled secondary antibodies were used for H2A and anti-TSN, respectively. Both proteins are mainly localized in the nucleus.Hossain MJ, Korde R, Singh PK, Kanodia S, Ranjan R, Ram G, Kalsey GS, Singh R, Malhotra P. Plasmodium falciparum Tudor Staphylococcal Nuclease interacting proteins suggest its role in nuclear as well as splicing processes. Gene. 2010 468(1-2):48-57. PMID: