Normal production of male and female gametocytes. Normal rates of male gamete formation as measured by the number of exflagellating male gametocytes. Male gametes showed reduced motility and fertility, with 50% of male gametes being immotile (see also 'Additional information phenotype').

Normal production of male and female gametocytes. Normal rates of male gamete formation as measured by the number of exflagellating male gametocytes. Male gametes showed reduced motility and fertility, with 50% of male gametes being immotile. The fertilisation rate as measured by the in vitro formation of ookinete was 20% compared to 70-80% in wild type gametes.

The fertilisation rate of gametes as measured by the in vitro formation of ookinete was 20% compared to 70-80% in wild type gametes. Ookinetes formed in vivo during a mosquito feed are able to give rise to a significant number of oocysts and generate normal sporozoites that are infectious to mice.

The fertilisation rate of gametes as measured by the in vitro formation of ookinete was 20% compared to 70-80% in wild type gametes. Ookinetes formed in vivo during a mosquito feed are able to give rise to a significant number of oocysts and generate normal sporozoites that are infectious to mice.

The fertilisation rate of gametes as measured by the in vitro formation of ookinete was 20% compared to 70-80% in wild type gametes. Ookinetes formed in vivo during a mosquito feed are able to give rise to a significant number of oocysts and generate normal sporozoites that are infectious to mice.