Disruptability [+]

Species Disruptability Reference Submitter
P. berghei ANKA
Possible
RMgm-1368 Imported from RMgmDB
P. falciparum 3D7
Possible
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. berghei ANKA Asexual
Difference from wild-type
RMgm-1368
Reduced parasite multiplication rate (PMR): 36%
Imported from RMgmDB
P. falciparum 3D7 Asexual
Attenuated
34756057 (Knock down) Theo Sanderson, Francis Crick Institute
P. berghei ANKA Gametocyte
Difference from wild-type
RMgm-1368
Strongly reduced exflagellation
Imported from RMgmDB
P. falciparum 3D7 Gametocyte
No difference
34756057 (Knock down) Theo Sanderson, Francis Crick Institute
P. berghei ANKA Sporozoite
Difference from wild-type
RMgm-1368
No sporozoites in vivo
Imported from RMgmDB
P. berghei ANKA Liver
Difference from wild-type
RMgm-1368
No transmission by bite of infected mosquitoes
Imported from RMgmDB

More information