Disruptability [+]

Species Disruptability Reference Submitter
P. berghei ANKA
Possible
RMgm-1147 Imported from RMgmDB
P. berghei ANKA
Possible
PlasmoGEM (Barseq) PlasmoGEM

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. berghei ANKA Asexual
No difference
RMgm-1147 Imported from RMgmDB
P. berghei ANKA Asexual
No difference
PlasmoGEM (Barseq) PlasmoGEM
P. berghei ANKA Gametocyte
No difference
RMgm-1147 Imported from RMgmDB
P. berghei ANKA Ookinete
No difference
RMgm-1147 Imported from RMgmDB
P. berghei ANKA Oocyst
Difference from wild-type
RMgm-1147
Oocyst are produced in normal numbers. Although oocysts in the mutant were established in high numbers, they never produced sporozoites and remained empty throughout the course of the infection. On a molecular level, mutant oocysts are characterized by a lack of DNA replication and expression of the sporozoite surface marker circumsporozoite protein (CSP).
Imported from RMgmDB
P. berghei ANKA Sporozoite
Difference from wild-type
RMgm-1147
No sporozoite formation
Imported from RMgmDB
P. berghei ANKA Liver
Difference from wild-type
RMgm-1147
No sporozoite formation
Imported from RMgmDB

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